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Cat. No.: HY-176231

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PRMT5-IN-51

PRMT5-IN-51 (compound 16–19F) is a potent PRMT5 inhibitor. PRMT5-IN-51 shows antiproliferative activity.

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CAS No.: 3064668-92-1
Formule: C₁₈H₁₆ClN₅O
Masse moléculaire:353.81

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

PRMT5-IN-51 Chemical Structure

CAS No.: 3064668-92-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

PRMT5-IN-51 (compound 16–19F) is a potent PRMT5 inhibitor. PRMT5-IN-51 shows antiproliferative activity^[1].

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Chemical Information

CAS No. 3064668-92-1
Masse moléculaire 353.81
Formule C₁₈H₁₆ClN₅O
SMILES

O=C(N1CC2=CC=C(C(N)=NC(N)=N3)C3=C2)CCC4=C1C(Cl)=CC=C4
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Shen Z, et al. Discovery and Mechanism of 16-19F, a Novel Synthetic Lethal Inhibitor of the PRMT5•MTA Complex in MTAP-Deleted Cancer Cells. ACS Chem Biol. 2025 Jun 20;20(6):1333-1346. [Content Brief]

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Calculateur de molarité

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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PRMT5-IN-51

Voir tous les produits spécifiques à Isoform Histone Methyltransferase

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

PRMT5-IN-51 Related Classifications

HY-176231 Related Classifications

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