PROTAC eEF2K degrader-1
Based on 1 Customer Validation
PROTAC eEF2K degrader-1 (Compound 11l) is an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells. PROTAC eEF2K degrader-1 mediates eEF2K degradation.
(Pink: CaMK III/eEF-2K ligand (HY-184950); Blue: Cereblon ligand (HY-103596); Black: linker).
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- Pureté: 98.64%
- CAS No.: 2458170-54-0
- Formule: C31H33N9O11
- Masse moléculaire:707.65
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Stockage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
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CaMK III/eEF-2K |
Chemical Information
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CAS No. 2458170-54-0
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Appearance Solid
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Masse moléculaire 707.65
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Formule C31H33N9O11
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Color White to off-white
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SMILES
CCN1C(N(C(C2=C1N=C(C(C(N)=O)=C2)N)=O)CC(NCCOCCNC(COC3=CC=CC4=C3C(N(C4=O)C5CCC(NC5=O)=O)=O)=O)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvant et solubilité
DMSO : 25 mg/mL (35.33 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4131 mL | 7.0656 mL | 14.1313 mL | 35.3282 mL |
| 5 mM | 0.2826 mL | 1.4131 mL | 2.8263 mL | 7.0656 mL | |
| 10 mM | 0.1413 mL | 0.7066 mL | 1.4131 mL | 3.5328 mL | |
| 15 mM | 0.0942 mL | 0.4710 mL | 0.9421 mL | 2.3552 mL | |
| 20 mM | 0.0707 mL | 0.3533 mL | 0.7066 mL | 1.7664 mL | |
| 25 mM | 0.0565 mL | 0.2826 mL | 0.5653 mL | 1.4131 mL | |
| 30 mM | 0.0471 mL | 0.2355 mL | 0.4710 mL | 1.1776 mL |
PROTAC eEF2K degrader-1 Related Classifications
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