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Vanucizumab

(Synonyms: Anti-Human VEGFA Recombinant Antibody; RO5520985)
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Based on 1 Customer Validation

Vanucizumab is a first-in-class, bispecific IgG1-like monoclonal antibody that simultaneously blocks VEGF-A and angiopoietin-2 (Ang-2) from interacting with their receptors. Vanucizumab has antiangiogenic and anticancer effects.

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  • Pureté: 95.12%
  • CAS No.: 1448221-05-3
  • Masse moléculaire:146.89 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vanucizumab
  • Experimental Validation Results for Vanucizumab
  • Experimental Validation Results for Vanucizumab
  • Experimental Validation Results for Vanucizumab
  • Vanucizumab Chemical Structure
    Vanucizumab Chemical Structure
CAS No.: 1448221-05-3
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Vanucizumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa-lambda with half-IG VL-CH1/VH-CK crossover

  • 1/16

    Immobilized Human VEGFA, His Tag can bind Vanucizumab. The EC50 for this effect is 4.575 ng/mL.

  • 1/16

    Immobilized Human ANGPT2, His Tag can bind Vanucizumab. The EC50 for this effect is 78.70 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 HeLa cells with Vanucizumab (HY-P99330, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.

  • Vanucizumab Chemical Structure
    1/16
  • Vanucizumab
  • Immobilized Human VEGFA, His Tag can bind Vanucizumab. The EC50 for this effect is 4.575 ng/mL.
  • Immobilized Human ANGPT2, His Tag can bind Vanucizumab. The EC50 for this effect is 78.70 ng/mL.
  • Flow cytometric analysis of 1X106 HeLa cells with Vanucizumab (HY-P99330, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.
  • IgG1-kappa-lambda with half-IG VL-CH1/VH-CK crossover