Xipamide-d6
Xipamide-d6 is the deuterated-labeled Xipamide (HY-W042301). Xipamide is an orally active carbonic anhydrase (CA) inhibitor and Na+/Cl--potassium cotransporter inhibitor, with diuretic and antihypertensive effects. Xipamide reduces NaCl reabsorption by inhibiting the Cl-/NaCO3- anion exchanger, promoting potassium and magnesium excretion while increasing calcium reabsorption. Xipamide is cleared primarily via the renal route and causes a transient decrease in glomerular filtration rate under specific conditions. Xipamide can be applied in research related to cardiovascular diseases, hypertension, advanced renal failure, and cirrhosis with ascites.
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- CAS No.: 1330262-09-3
- Formule: C15H9D6ClN2O4S
- Masse moléculaire:360.85
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
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CAs |
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1330262-09-3
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Unlabeled CAS 14293-44-8
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Masse moléculaire 360.85
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Formule C15H9D6ClN2O4S
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SMILES
C(NC1=C(C([2H])([2H])[2H])C=CC=C1C([2H])([2H])[2H])(=O)C2=CC(S(N)(=O)=O)=C(Cl)C=C2O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Xipamide-d6
- 1330262-09-3
- Isotope-Labeled Compounds
- Anion Exchangers
- Carbonic Anhydrase
- Endothelin Receptor
- CO2 hydration
- DIDS-sensitive LiCO3? influx
- K+/Cl? co-transport
- Na+/K+ co-transport
- anion-exchange inhibitor
- carbonic anhydrase inhibitor
- cardiovascular diseases
- catalytic zinc site
- hepatic urea synthesis
- sodium-dependent chloride/bicarbonate exchange
- Inhibitor
- inhibitor
- inhibit