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Art. -Nr.: HY-139003

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4'-Hydroxywarfarin

Name: 4'-Hydroxywarfarin
Brand: MedChemExpress
SKU: HY-139003
Price: 263.00 USD
Availability: InStock
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4′-Hydroxywarfarin is a regioisomeric phenolic derivative of Warfarin (HY-B0687). 4′-Hydroxywarfarin is a major metabolite of Warfarin in mammals and serves as a metabolic probe for the diversity of cytochrome P-450 isoenzymes.

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Reinheit : 99.59%
CAS. Nr.: 24579-14-4
Formel: C₁₉H₁₆O₅
Molecular Weight:324.33

Speicherung:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

4'-Hydroxywarfarin Chemical Structure

CAS. Nr.: 24579-14-4

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

Alle Cytochrome P450 Isoform-spezifische Produkte anzeigen :

In Vitro

4′-Hydroxywarfarin (compound W4) (10 mM) undergoes concentration-dependent upward pK_a shifts when complexed with neutral β-Cyclodextrin (HY-107201)^[1].
4′-Hydroxywarfarin (0.5 mg/mL; 6 d) is produced via biotransformation of Warfarin (HY-B0687) by Cunninghamella bainieri (UI-3065) cell suspension cultures, yielding 2 mg of pure metabolite^[2].
4′-Hydroxywarfarin (12.5 mg per flask; 12-48 h) is produced from 4′-deuterowarfarin by Cunninghamella bainieri (UI-3065) cell suspension cultures with an average 80% deuterium migration and retention^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 24579-14-4
Appearance Solid
Molecular Weight 324.33
Formel C₁₉H₁₆O₅
SMILES

O=C1C(C(C2=CC=C(O)C=C2)CC(C)=O)=C(O)C3=CC=CC=C3O1
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (287 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Nowak, Paweł M, et al. Modulation of pK _a by cyclodextrins; subtle structural changes induce spectacularly different behaviors. RSC Adv., 5(95), 77545–77552.

[2]. Rizzo JD, et al. Microbial models of mammalian metabolism: conversion of warfarin to 4'-hydroxywarfarin using Cunninghamella bainieri. Journal of pharmaceutical sciences. 1989 Mar;78(3):183-9.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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