Anticancer agent 91
Anticancer agent 91 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor and antiviral activity. Anticancer agent 91 has high inhibition against the two cell line from CNS cancer (SF-539 and SNB-75).
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- CAS. Nr.: 2977251-00-4
- Formel: C33H32N2O10S3
- Molecular Weight:712.81
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
In Vitro
Anticancer agent 91 (compound 6a) (0.01 mM; 24 h) has low cytotoxicity, shows high inhibition against SF-539, SNB-75 and HCT-116[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
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Cell Line:FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cell lines
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Concentration:0-200 μg/mL
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Incubation Time:24 hours
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Result:Showed nontoxic under the doses of 90 μg/mL against FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cells, respectively.
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Cell Line:SF-539, SNB-75
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Concentration:0.01 mM
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Incubation Time:24 hours
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Result:Inhibited SF-539, SNB-75 and HCT-116 cell viability by 28.19%, 25.40%, respectively.
Chemical Information
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CAS. Nr. 2977251-00-4
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Molecular Weight 712.81
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Formel C33H32N2O10S3
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SMILES
O=C(C1=C(N)C(C2=NC3=CC=CC=C3S2)=C(S[C@H]4[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@](OC(C)=O)([H])[C@@H](COC(C)=O)O4)S1)C5=CC=C(C)C=C5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Anticancer agent 91 Related Classifications
HY-151592 Related Classifications
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