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Art. -Nr.: HY-107331

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Chlorproguanil

Chlorproguanil is an antifolate with an IC₅₀ of 4.68 μM against Plasmodium falciparum female gamete formation. Chlorproguanil can be used for the research of malaria.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 537-21-3
Formel: C₁₁H₁₅Cl₂N₅
Molecular Weight:288.18

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Chlorproguanil Chemical Structure

CAS. Nr.: 537-21-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
- Clinical Trial
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Chlorproguanil is an antifolate with an IC₅₀ of 4.68 μM against Plasmodium falciparum female gamete formation. Chlorproguanil can be used for the research of malaria^[1].

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In Vitro

Chlorproguanil (0-25 μM; 48 h) inhibits P. falciparum stage V female gametocyte activation with a mean IC₅₀ of 4.68 μM following 48 h incubation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991			2011-05	PHASE1

Chemical Information

CAS. Nr. 537-21-3
Molecular Weight 288.18
Formel C₁₁H₁₅Cl₂N₅
SMILES

ClC1=CC=C(C=C1Cl)NC(=N)NC(=N)NC(C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Miguel-Blanco C, et al. Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation. Antimicrob Agents Chemother. 2015;59(6):3298-305. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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