EP009
EP009 is a JAK3 inhibitor that selectively inhibits IL-2-mediated JAK3 tyrosine phosphorylation (IC50=10-20 μM in Kit225 cells) without affecting IL-3-induced JAK2 phosphorylation (up to 50 μM in BaF/3 cells). EP009 significantly reduced Kit225 cell viability (72 h, LD50=5.0 μM) while having no effect on BaF/3 cells..
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- CAS. Nr.: 1462951-30-9
- Formel: C14H24O2
- Molecular Weight:224.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
JAK3[1]
Chemical Information
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CAS. Nr. 1462951-30-9
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Molecular Weight 224.34
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Formel C14H24O2
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SMILES
O=C1C(CCCCCCCCCC1=C)CO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
EP009 Related Classifications
HY-121874 Related Classifications
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