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Art. -Nr.: HY-118331

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Kazusamycin B

(Synonyms: PD 124895; CL-1957E)

Kazusamycin B is an antibiotic that could be isolated from the fermentation broth of Streptomyces sp. No. 81-484. Kazusamycin B inhibits cell growth and arrests cell cycle at G1 phase. Kazusamycin B can be used in research of cancer.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 107140-30-7
Formel: C₃₂H₄₆O₇
Molecular Weight:542.70

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Kazusamycin B Chemical Structure

CAS. Nr.: 107140-30-7

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle Antibiotic Isoform-spezifische Produkte anzeigen :

In Vitro

Kazusamycin B (PD 124895; 5 ng/mL; 24 h; 1210 cells) has cell cytotoxicity in a time-dependent manner and arrests cell cycle at G1 phase^[2].
Kazusamycin B (5-50 ng/mL; 0-6 h; 1210 cells) B inhibits RNA synthesis moderately but specifically at 2 hours^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cycle Analysis^[2]

Cell Line:

1210 cells
Concentration:

5 ng/mL
Incubation Time:

24 h
Result:

Arrested cell cycle at G1 phase at 4 hours.

Chemical Information

CAS. Nr. 107140-30-7
Molecular Weight 542.70
Formel C₃₂H₄₆O₇
SMILES

O=C(/C=C(CC(C(C(C(C(/C=C(/C=C/CC(/C=C(/C=C/C1C(C=CC(O1)=O)C)C)C)C)CO)=O)C)O)C)\C)O
Synonyms

PD 124895; CL-1957E
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Funaishi K, et, al. Kazusamycin B, a novel antitumor antibiotic. J Antibiot (Tokyo). 1987 Jun;40(6):778-85. [Content Brief]

[2]. Takamiya K, et, al. The effect of kazusamycin B on the cell cycle and morphology of cultured L1210 cells. J Antibiot (Tokyo). 1988 Dec;41(12):1854-61. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
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- In Vitro
Chemical Information
Reinheit & Dokumentation
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Kazusamycin B

Alle Antibiotic Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Kazusamycin B Related Classifications

HY-118331 Related Classifications