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Art. -Nr.: HY-13837

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P4Q-391

P4Q-391 is a Plasmodium cytochrome bc1 complex inhibitor with antimalarial activity. P4Q-391 is promising for research of parasites.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 1374758-06-1
Formel: C₂₄H₁₆ClF₄NO₄
Molecular Weight:493.83

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

P4Q-391 Chemical Structure

CAS. Nr.: 1374758-06-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

P4Q-391 is a Plasmodium cytochrome bc1 complex inhibitor with antimalarial activity. P4Q-391 is promising for research of parasites^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
J774	EC₅₀	>20.2 μM Compound: 7, P4Q-391	Cytotoxicity against mouse J774 cells after 72 hrs by CellTiter 96 assay Cytotoxicity against mouse J774 cells after 72 hrs by CellTiter 96 assay	[PMID: 25148516]
J774	EC₅₀	20.2 μM Compound: 7, P4Q-391	Cytotoxicity against mouse J774 cells after 72 hrs by CellTiter 96 assay Cytotoxicity against mouse J774 cells after 72 hrs by CellTiter 96 assay	[PMID: 25148516]

Chemical Information

CAS. Nr. 1374758-06-1
Molecular Weight 493.83
Formel C₂₄H₁₆ClF₄NO₄
SMILES

O=C1C(C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2F)=C(C)NC4=C1C=C(Cl)C(OC)=C4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Cross RM, et al. Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium. J Med Chem. 2014 Nov 13;57(21):8860-79. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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Biologische Aktivität
- Beschreibung
Chemical Information
Reinheit & Dokumentation
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P4Q-391

Alle Parasite Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

P4Q-391 Related Classifications

HY-13837 Related Classifications