TrkA
TrkA, encoded by the NTRK1 gene, is the high-affinity receptor tyrosine kinase for nerve growth factor (NGF). Ligand-induced dimerization activates the intracellular kinase and initiates RAS/MAPK, PI3K/AKT, and PLC-gamma signaling that supports survival and differentiation of sympathetic and sensory neurons during development. Inactivating mutations of NTRK1 cause congenital insensitivity to pain with anhidrosis, a rare disorder characterized by loss of pain perception and impaired thermoregulation. Chromosomal rearrangements generating NTRK1 fusion proteins with constitutive kinase activity occur in papillary thyroid carcinoma, infantile fibrosarcoma, and other tumors, and are targetable with TRK inhibitors such as larotrectinib and entrectinib.
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TrkA Recombinant Proteins (15)
TrkA Protein, Human (HEK293, His)
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Art. -Nr.: HY-P73457
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
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TrkA Protein, Mouse (HEK293, His)
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Art. -Nr.: HY-P76116
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
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TrkA Protein, Human (HEK293)
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Art. -Nr.: HY-P7308
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophic Tyrosine Kinase, Receptor, Type 1; Tyrosine Kinase Receptor; TRK1-Transforming Tyrosine Kinase Protein; Oncogene TRK; Tropomyosin Receptor Kinase A; TRK1; Tropomyosin-Related Kinase A
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TrkA Protein, Canine (HEK293, His)
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Art. -Nr.: HY-P73456
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
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TrkA Protein, Mouse (HEK293, Fc)
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Art. -Nr.: HY-P76115
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
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TrkA Protein, Canine (HEK293, Fc)
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Art. -Nr.: HY-P73578
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
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TrkA Protein, Rat (HEK293, His)
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Art. -Nr.: HY-P73460
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
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TrkA Protein, Rabbit (HEK293, His)
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Art. -Nr.: HY-P73577
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
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TrkA Protein, Human (sf9, Flag, Avi)
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Art. -Nr.: HY-P705892
Reinheit: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophic Tyrosine Kinase, Receptor, Type 1; Tyrosine Kinase Receptor; TRK1-Transforming Tyrosine Kinase Protein; Oncogene TRK; Tropomyosin Receptor Kinase A; TRK1; Tropomyosin-Related Kinase A
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TrkA Protein, Human (HEK293, His-Fc)
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Art. -Nr.: HY-P73458
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
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TrkA Protein, Rat (HEK293, Fc)
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Art. -Nr.: HY-P73459
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
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TrkA Protein, Human (Biotinylated, sf9, Flag, Avi)
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Art. -Nr.: HY-P702762
Reinheit: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
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TrkA Protein, Human (HEK293, mFc)
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Art. -Nr.: HY-P704311
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
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TrkA Protein, Human (211a.a, HEK293, mFc)
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Art. -Nr.: HY-P704941
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophic Tyrosine Kinase, Receptor, Type 1; Tyrosine Kinase Receptor; TRK1-Transforming Tyrosine Kinase Protein; Oncogene TRK; Tropomyosin Receptor Kinase A; TRK1; Tropomyosin-Related Kinase A
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TrkA Protein, Human (Active, sf9, His-GST)
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Art. -Nr.: HY-P706108
Reinheit: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophic Tyrosine Kinase, Receptor, Type 1; Tyrosine Kinase Receptor; TRK1-Transforming Tyrosine Kinase Protein; Oncogene TRK; Tropomyosin Receptor Kinase A; TRK1; Tropomyosin-Related Kinase A
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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Synonyms: Serpin B6; Cytoplasmic Antiproteinase; cap; Peptidase Inhibitor
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
