Thalidomide-O-PNB ester
Thalidomide-O-PNB ester is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-PNB ester can be linked to a target protein ligand via a linker to form a PROTAC.
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- Formel: C21H15N3O9
- Molecular Weight:453.36
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 453.36
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Formel C21H15N3O9
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SMILES
O=C1CCC(C(N1)=O)N2C(C3=C(C(OCC(OC4=CC=C([N+]([O-])=O)C=C4)=O)=CC=C3)C2=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Thalidomide-O-PNB ester Related Classifications
HY-W1130334 Related Classifications
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