Thioredoxin reductase
Based on 1 Customer Validation
Thioredoxin reductase (TrxR) is a selenocysteine-containing NADPH-dependent disulfide oxidoreductase derived from rat liver that utilizes NADPH to reduce oxidized thioredoxin. Thioredoxin reductase can utilize the reducing capacity of human erythrocytes to study the uptake and reduction of α-Lipoic Acid (HY-N0492), and can also be used to investigate the activation mechanism of transglutaminase 2 (TG2) in the extracellular matrix using thioredoxin.
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- CAS. Nr.: 9074-14-0
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
In Vitro
Thioredoxin reductase (TrxR) is rapidly inactivated in serum by NADPH or NADPH-regenerating systems, and in the serum of H22 hepatoma-bearing mice, endogenous electrophilic compounds PpIX and 4-HNE are increased[1].
Thioredoxin reductase (from rat liver) can utilize the reducing capacity of human erythrocytes to study the uptake and reduction of α-lipoic acid[2].
Thioredoxin reductase (from rat liver) is used to study the activation mechanism of transglutaminase 2 (TG2) in the extracellular matrix using thioredoxin[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 9074-14-0
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Thioredoxin reductase]
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Synonyms
TrxR
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Data Sheet (265 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Thioredoxin reductase Related Classifications
HY-P2759 Related Classifications
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