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Art. -Nr.: HY-182553

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USP30-IN-2

USP30-IN-2, a fused pyrroline, is an USP30 inhibitor with an IC₅₀ <0.1 μM. USP30-IN-2 is expected to promote mitophagy and restore mitochondrial health. USP30-IN-2 can be used for research on Parkinson's disease.

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CAS. Nr.: 2414580-72-4
Formel: C₂₂H₁₉N₅O₂
Molecular Weight:385.42

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

USP30-IN-2 Chemical Structure

CAS. Nr.: 2414580-72-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
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Verweise
Calculators
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Biologische Aktivität

Beschreibung

IC₅₀ & Target

^[1]

USP30

<0.1 μM (IC₅₀)

Alle Deubiquitinase Isoform-spezifische Produkte anzeigen :

In Vitro

USP30-IN-2 (Compound 13-a) exhibits an IC₅₀ value of less than 0.1 μM against USP30 (0.2 nM) in Ubiquitin-Rhodamine 110 assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS. Nr. 2414580-72-4
Molecular Weight 385.42
Formel C₂₂H₁₉N₅O₂
SMILES

O=C(C1=CC(C2=C(C=CC=C2)OC3=CC=CC=C3)=NN1)N[C@@H]4[C@@]5([H])[C@](N(C4)C#N)([H])C5
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Buckmelter AJ, et al. Fused pyrrolines which act as ubiquitin-specific protease 30 (usp30) inhibitors. United States, WO2020072964 A.2020-07-29.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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USP30-IN-2

Alle Deubiquitinase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

IC50 & Target

In Vitro

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

USP30-IN-2 Related Classifications

HY-182553 Related Classifications

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Keywords

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