Zedoalactone B
Zedoalactone B is an anti-Babesial agent with an IC50 of 1.6 μg/mL against Babesia gibsoni. Zedoalactone B inhibits NO production with an IC50 of 23.8 μM.
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- CAS. Nr.: 170384-81-3
- Formel: C15H20O5
- Molecular Weight:280.32
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
1.3 μM
Compound: 22
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
|
[PMID: 23755850] |
Chemical Information
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CAS. Nr. 170384-81-3
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Molecular Weight 280.32
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Formel C15H20O5
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SMILES
O[C@]([C@](O)(C=C1OC2=O)C)(CC[C@](O)3C)[C@]3([H])CC1=C2C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Kasahara K, et al. Anti-babesial compounds from Curcuma zedoaria. Planta Med. 2005 May;71(5):482-4. [Content Brief]
[2]. Lou Y, et al. Guaiane-type sesquiterpenes from Curcuma wenyujin and their inhibitory effects on nitric oxide production. J Asian Nat Prod Res. 2009 Aug;11(8):737-47. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)