Glidobactin A
Glidobactin A is an acyl peptide antibiotic. Glidobactin A has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice.
For research use only. We do not sell to patients.
- CAS No.: 108351-50-4
- Formula: C27H44N4O6
- Molecular Weight:520.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
33.3 nM
Compound: glidobactin A
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Cytotoxicity against human HCT116 cells assessed as cell viability after 5 days by MTT assay relative to control
Cytotoxicity against human HCT116 cells assessed as cell viability after 5 days by MTT assay relative to control
|
[PMID: 22909174] |
| MIA PaCa-2 | IC50 |
0.069 μM
Compound: 1
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Inhibition of 20S proteasome in human MIAPaCa2 cells after 90 mins by fluorescence-based colorimetry
Inhibition of 20S proteasome in human MIAPaCa2 cells after 90 mins by fluorescence-based colorimetry
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[PMID: 23095088] |
| MIA PaCa-2 | IC50 |
7 x 10-3 μM
Compound: 1
|
Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 23095088] |
| MIA PaCa-2 | IC50 |
7 nM
Compound: 1
|
Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 23095088] |
Chemical Information
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CAS No. 108351-50-4
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Molecular Weight 520.66
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Formula C27H44N4O6
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SMILES
CCCCCCC/C=C/C=C/C(N[C@H](C(N[C@@H]1C(N[C@@H](C)/C=C/C(NCC[C@H](O)C1)=O)=O)=O)[C@H](O)C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)