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KN-93

104 Cited Publications
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Based on 104 publication(s) in Google Scholar

KN-93 is a cell-permeable, reversible and competitive inhibitor calmodulin-dependent kinase type II (CaMKII) with a Ki of 370 nM.

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  • Pureté: 99.54%
  • CAS No.: 139298-40-1
  • Formule: C26H29ClN2O4S
  • Masse moléculaire:501.04
  • Stockage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 2 years , -20°C, 1 year
  • KN-93 Chemical Structure
    KN-93 Chemical Structure
  • Experimental Validation Results for KN-93
  • Experimental Validation Results for KN-93
  • Experimental Validation Results for KN-93
  • Experimental Validation Results for KN-93
CAS No.: 139298-40-1
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  • KN-93 Chemical Structure
    KN-93 Chemical Structure
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  • 1/16

    KN-93 purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2020 Feb;41(2):218-228. [Abstract]

    Customer Validation
     HUVECs are pretreated with KN93 for 1 h, followed by ZYZ-803 (1 μM) for 30 min. Protein levels are assessed by Western blot.

  • 1/16

    KN-93 purchased from MedChemExpress. Usage Cited in: Diabetes. 2018 Sep;67(9):1748-1760. [Abstract]

    Customer Validation
     Immunoblotting analysis of PCK1, G6Pase, and phospho-CaMKIIγ proteins in NTG and HCTG hepatocytes in response to PGF2α and in the presence or absence of KN-93 treatment.

  • 1/16

    KN-93 purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2018 Apr 12:9:362. [Abstract]

    Customer Validation
     MK 733-increased biotinylated α7nAChR protein is blocked by the addition of KN93 (P<0.01, n=6 mice).

  • 1/16

    KN-93 purchased from MedChemExpress. Usage Cited in: Exp Cell Res. 2018 Mar 15;364(2):198-207. [Abstract]

    Customer Validation
     Western blot analysis of β-catenin protein level in HEK 293T cells stimulated for 12h with rAGR2 (100 ng/mL) coupled with or without KN93 (10 μM).

  • KN-93