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Cat. No.: HY-B0500A

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Alverine

Name: Alverine
Brand: MedChemExpress
SKU: HY-B0500A
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1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Alverine citrate is a 5-HT_1A receptor antagonist, with an IC₅₀ of 101 nM.

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CAS No.: 150-59-4
Formule: C₂₀H₂₇N
Masse moléculaire:281.44

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Alverine Chemical Structure

CAS No.: 150-59-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- Essai clinique
Chemical Information
Publications (1)
Protocole (1)
Pureté et documentation
Références
Calculators
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Activité biologique

Description

Alverine citrate is a 5-HT_1A receptor antagonist, with an IC₅₀ of 101 nM.

IC₅₀ & Target

5-HT_1A Receptor

Voir tous les produits spécifiques à Isoform 5-HT Receptor :

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 150-59-4
Masse moléculaire 281.44
Formule C₂₀H₂₇N
SMILES

CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Biochem Biophys Res Commun

Combinatorial screening of a panel of FDA-approved drugs identifies several candidates with anti-Ebola activities. [Abstract]

2020 Feb 19;522(4):862-868. PMID: 31806372

Protocole

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Coelho, A.M., et al., Rectal antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtype. J Pharm Pharmacol, 2001. 53(10): p. 1419-26. [Content Brief]

[2]. Hayase, M., et al., Evolving mechanisms of action of alverine citrate on phasic smooth muscles. Br J Pharmacol, 2007. 152(8): p. 1228-38. [Content Brief]

Calculators

Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Alverine

1 Cited Publications

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Activité biologique
- Description
- IC₅₀ & Target
- Essai clinique
Chemical Information
Publications (1)
Protocole
Pureté et documentation
Références

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Alverine

Publications Citing Use of MedChemExpress (MCE) Alverine

Voir tous les produits spécifiques à Isoform 5-HT Receptor