AP-22161
AP22161 is a potent and selective Src SH2 domain inhibitor with an IC50 of 0.24 µM. AP22161 exhibits >120-fold selectivity over Yes SH2 (IC50 = 29.38 µM) and ZAP SH2 (IC50 = 421.86 µM). AP22161 inhibits Src-dependent cellular activity and diminishes osteoclast resorptive activity. AP22161 can be used for osteoporosis research.
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- CAS No.: 268741-42-0
- Formule: C32H39N3O7
- Masse moléculaire:577.67
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Yes SH2 29.38 μM (IC50) |
ZAP SH2 421.86 μM (IC50) |
Chemical Information
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CAS No. 268741-42-0
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Masse moléculaire 577.67
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Formule C32H39N3O7
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SMILES
O=C(O)C1=CC=C(C[C@H](NC(C)=O)C(N[C@H]2CCCCC3=CC(OCC4CCCCC4)=C(C(N)=O)C=C32)=O)C=C1C=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AP-22161 Related Classifications
HY-123394 Related Classifications
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