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Coppersensor 1

34 Cited Publications
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Based on 34 publication(s) in Google Scholar

Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu+ with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu+) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases.

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  • Pureté: 97.74%
  • CAS No.: 874748-20-6
  • Formule: C30H50BF2N3S4
  • Masse moléculaire:629.81
  • Stockage:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • Coppersensor 1 Chemical Structure
    Coppersensor 1 Chemical Structure
  • Experimental Validation Results for Coppersensor 1
  • Experimental Validation Results for Coppersensor 1
  • Experimental Validation Results for Coppersensor 1
  • Experimental Validation Results for Coppersensor 1
  • Experimental Validation Results for Coppersensor 1
  • Experimental Validation Results for Coppersensor 1
  • Experimental Validation Results for Coppersensor 1
  • Experimental Validation Results for Coppersensor 1
CAS No.: 874748-20-6
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Cell Imaging/StainingRT-PCR
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  • Coppersensor 1 Chemical Structure
    Coppersensor 1 Chemical Structure
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    Coppersensor 1 purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul 13:e02501. [Abstract]

    Customer Validation
     Analysis of monovalent copper ion levels in TRIM21‐knockdown KYSE30 cells following 0.5 mm CuSO4 treatment (CS1, 5 μM, 10 min).

  • 1/16

    Coppersensor 1 purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul 13:e02501. [Abstract]

    Customer Validation
     Analysis of monovalent copper ion levels in TRIM21‐knockdown KYSE450 cells following 0.5 mm CuSO4 treatment (CS1, 5 μM, 10 min).

  • 1/16

    Coppersensor 1 purchased from MedChemExpress. Usage Cited in: Stem Cell Res Ther. 2025 Sep 29;16(1):526. [Abstract]

    Customer Validation
     Copper sensor probe (Red) (5 μM; 30 min) was used.

  • 1/16

    Coppersensor 1 purchased from MedChemExpress. Usage Cited in: Int J Mol Med. 2025 Oct;56(4):154. [Abstract]

    Customer Validation
     Copper sensor 1 (5 μM; 30 min). Fluorescence staining indicated that intracellular copper ion levels were elevated in U87 and U251 cells following SDF2 knockdown compared with those in control cells (n = 3, scale bar, 50 µm).

  • 1/16

    Coppersensor 1 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2024 Aug 13;15(1):6947. [Abstract]

    Customer Validation
     RNA-qPCR fold-changes of select transcripts 4 h post-supplementation of 500 nM CuGTSM or 5 µM Coppersensor-1 (CS1) relative to DMSO treated A549 cells.

  • 1/16

    Coppersensor 1 purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2024 May 11:26:101087. [Abstract]

    Customer Validation
     Representative fluorescent images of intracellular Cu⁺ distribution. Upon exposure to HL stimulation for 12 h, NIH-3T3 cells were treated with CuONPs or CuO@PS, both containing CuONPs at concentrations of 5 μg/mL, for 12 h, and then the cells were washed and detected with Cu⁺ probe Coppersensor-1 (CS-1, red) (5 μM; 20 min) at different time points. Lysosomes were stained with lysotracker (green). Scale bar, 10 μm.

  • 1/16

    Coppersensor 1 purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2024 Oct 30;25(21):11657. [Abstract]

    Customer Validation
     Copper content was measured using Coppersensor 1 (5 μM; 30 min) and detected by fluorescence microscopy.

  • 1/16

    Coppersensor 1 purchased from MedChemExpress. Usage Cited in: BMC Pharmacol Toxicol. 2024 Aug 21;25(1):54. [Abstract]

    Customer Validation
     Levels of copper in cells were labeled by Coppersensor 1 (5 μM; 15 min).

  • Coppersensor 1