EP009
EP009 is a JAK3 inhibitor that selectively inhibits IL-2-mediated JAK3 tyrosine phosphorylation (IC50=10-20 μM in Kit225 cells) without affecting IL-3-induced JAK2 phosphorylation (up to 50 μM in BaF/3 cells). EP009 significantly reduced Kit225 cell viability (72 h, LD50=5.0 μM) while having no effect on BaF/3 cells..
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- CAS No.: 1462951-30-9
- Formule: C14H24O2
- Masse moléculaire:224.34
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
JAK3[1]
Chemical Information
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CAS No. 1462951-30-9
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Masse moléculaire 224.34
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Formule C14H24O2
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SMILES
O=C1C(CCCCCCCCCC1=C)CO
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)