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Evabosmig

(Synonyms: AGA2118)
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Evabosmig (AGA2118) is a humanized bispecific monoclonal antibody targeting sclerostin (SOST/sclerostin) and DKK1. SOST and DKK1 are two key secreted negative regulators of the intramedullary Wnt/β-catenin pathway. Evabosmig possesses activities to induce bone formation, inhibit bone resorption and increase bone mineral density. Evabosmig is applicable for research related to osteoporosis.

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  • Pureté : 97.91%
  • CAS No.: 3061142-96-6
  • Masse moléculaire:145.18 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Evabosmig
  • Experimental Validation Results for Evabosmig
  • Experimental Validation Results for Evabosmig
  • Evabosmig Chemical Structure
    Evabosmig Chemical Structure
CAS No.: 3061142-96-6
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Evabosmig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG4-kappa

  • 1/16

    Immobilized SOST Protein, Human (HEK293, HY-P70756) can bind Evabosmig. The ED50 for this effect is 361 ng/mL.

  • 1/16

    Loaded Evabosmig on biosensor, can bind DKK-1 Protein, Human (HEK293, HY-P7155A) with an affinity constant of 6.75E-10 M as determined in BLI assay.

  • Evabosmig Chemical Structure
    1/16
  • Evabosmig
  • Immobilized SOST Protein, Human (HEK293, HY-P70756) can bind Evabosmig. The ED50 for this effect is 361 ng/mL.
  • Loaded Evabosmig on biosensor, can bind DKK-1 Protein, Human (HEK293, HY-P7155A) with an affinity constant of 6.75E-10 M as determined in BLI assay.
  • IgG4-kappa