LUF8100
Based on 1 Customer Validation
LUF8100 is a dual-target antagonist of CCR2/CCR5 with pKi values for CCR2 and CCR5 of 5.23 and 4.97 respectively. LUF8100 can be used for research on immune homeostasis and cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 98.64%
- CAS No.: 2954281-30-0
- Formule: C18H18ClF3N2O2S
- Masse moléculaire:418.86
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Activité biologique
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CCR2 5.23 (pKi) |
CCR5 4.97 (pKi) |
Chemical Information
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CAS No. 2954281-30-0
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Appearance Solid
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Masse moléculaire 418.86
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Formule C18H18ClF3N2O2S
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Color Off-white to pink
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SMILES
O=S(NC1=CC(N2CCCCC2)=CC=C1)(C3=CC=C(Cl)C(C(F)(F)F)=C3)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : ≥ 100 mg/mL (238.74 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3874 mL | 11.9372 mL | 23.8743 mL | 59.6858 mL |
| 5 mM | 0.4775 mL | 2.3874 mL | 4.7749 mL | 11.9372 mL | |
| 10 mM | 0.2387 mL | 1.1937 mL | 2.3874 mL | 5.9686 mL | |
| 15 mM | 0.1592 mL | 0.7958 mL | 1.5916 mL | 3.9791 mL | |
| 20 mM | 0.1194 mL | 0.5969 mL | 1.1937 mL | 2.9843 mL | |
| 25 mM | 0.0955 mL | 0.4775 mL | 0.9550 mL | 2.3874 mL | |
| 30 mM | 0.0796 mL | 0.3979 mL | 0.7958 mL | 1.9895 mL | |
| 40 mM | 0.0597 mL | 0.2984 mL | 0.5969 mL | 1.4921 mL | |
| 50 mM | 0.0477 mL | 0.2387 mL | 0.4775 mL | 1.1937 mL | |
| 60 mM | 0.0398 mL | 0.1990 mL | 0.3979 mL | 0.9948 mL | |
| 80 mM | 0.0298 mL | 0.1492 mL | 0.2984 mL | 0.7461 mL | |
| 100 mM | 0.0239 mL | 0.1194 mL | 0.2387 mL | 0.5969 mL |