Mol4
Mol4 (AK-918/41759663) is a highly selective BCL-2 protein inhibitor (IC50=153.3 μM). Mol4 induces mitochondrial outer membrane permeabilization (MOMP) and cytochrome c release, showing significant antiproliferative activity against glioblastoma (U87-MG) cell lines. Mol4 is promising for research of BCL-2-dependent tumors (e.g., chronic lymphocytic leukemia).
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- CAS No.: 512800-53-2
- Formule: C30H20ClNO5S
- Masse moléculaire:542.00
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Chemical Information
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CAS No. 512800-53-2
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Masse moléculaire 542.00
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Formule C30H20ClNO5S
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SMILES
O=C(C1=CC2=C(C(N(C3=CC=C(SC4=CC=C(C)C=C4)C=C3)C2=O)=O)C=C1)OCC(C5=CC=C(Cl)C=C5)=O
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Synonyms
AK-918/41759663
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)