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Tecaginlimab

(Synonyms: BNT-312; DuoBody-CD40x-4-1BB; GEN1042)
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Tecaginlimab (BNT-312) is a Fc-inert bispecific antibody for dual targeting and conditional stimulation of CD40 and 4-1BB. Tecaginlimab can enhance priming and reactivation of tumor-specific immunity.

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  • Pureté: 99.00%
  • CAS No.: 2253891-70-0
  • Masse moléculaire:145.098 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Tecaginlimab
  • Experimental Validation Results for Tecaginlimab
  • Experimental Validation Results for Tecaginlimab
  • Tecaginlimab Chemical Structure
    Tecaginlimab Chemical Structure
CAS No.: 2253891-70-0
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Tecaginlimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Tecaginlimab on AHC2 biosensor, can bind 4-1BB/TNFRSF9 Protein, Human (HEK293, His, HY-P70678) with an affinity constant of 5.270E-11 M as determined in BLI assay.

  • 1/16

    Flow Cytometry analysis of Raji cells labelling CD40 (red) with Tecaginlimab (HY-P99572). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Tecaginlimab Chemical Structure
    1/16
  • Tecaginlimab
  • Loaded Tecaginlimab on AHC2 biosensor, can bind 4-1BB/TNFRSF9 Protein, Human (HEK293, His, HY-P70678) with an affinity constant of 5.270E-11 M as determined in BLI assay.
  • Flow Cytometry analysis of Raji cells labelling CD40 (red) with Tecaginlimab (HY-P99572). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).