2. GPCR/G Protein Anti-infection Neuronal Signaling Immunology/Inflammation Membrane Transporter/Ion Channel
  3. HCV TRP Channel Histamine Receptor
  4. Clemizole-d4

Clemizole-d4 is a deuterium labeled Clemizole. Clemizole is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication.

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Clemizole-d<sub>4</sub>

Clemizole-d4 화학구조

CAS No. : 1251554-64-9

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 견적 받기 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
Solution
10 mM * 1 mL in DMSO 견적 받기 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
Solid
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of Clemizole-d4:

Clemizole-d4 Related Antibodies

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View All TRP Channel Isoform Specific Products:

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TRPA1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TRPM8 TRPM2 TRPM3 TRPM4 TRPM7 TRPML1 TRPML2 TRPML3 TRPV1 TRPV2 TRPV3 TRPV4 TRPV6

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H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Clemizole-d4 is a deuterium labeled Clemizole. Clemizole is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

분자량

329.86

화학식

C19H16D4ClN3
CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

ClC1=C([2H])C([2H])=C(C([2H])=C1[2H])CN2C(CN3CCCC3)=NC4=CC=CC=C24
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 100 mg/mL (303.16 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0316 mL 15.1579 mL 30.3159 mL
5 mM 0.6063 mL 3.0316 mL 6.0632 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0316 mL 15.1579 mL 30.3159 mL 75.7897 mL
5 mM 0.6063 mL 3.0316 mL 6.0632 mL 15.1579 mL
10 mM 0.3032 mL 1.5158 mL 3.0316 mL 7.5790 mL
15 mM 0.2021 mL 1.0105 mL 2.0211 mL 5.0526 mL
20 mM 0.1516 mL 0.7579 mL 1.5158 mL 3.7895 mL
25 mM 0.1213 mL 0.6063 mL 1.2126 mL 3.0316 mL
30 mM 0.1011 mL 0.5053 mL 1.0105 mL 2.5263 mL
40 mM 0.0758 mL 0.3789 mL 0.7579 mL 1.8947 mL
50 mM 0.0606 mL 0.3032 mL 0.6063 mL 1.5158 mL
60 mM 0.0505 mL 0.2526 mL 0.5053 mL 1.2632 mL
80 mM 0.0379 mL 0.1895 mL 0.3789 mL 0.9474 mL
100 mM 0.0303 mL 0.1516 mL 0.3032 mL 0.7579 mL
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Clemizole-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Clemizole-d41251554-64-9HCVTRP ChannelHistamine ReceptorHepatitis C virusTransient receptor potential channelsDeuteriumH1 histamine receptorHCV replicationInhibitorinhibitorinhibit

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상품명:
Clemizole-d4
Cat. No.:
HY-30234S
수량:
MCE Japan Authorized Agent:

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