1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Cloxacillin sodium

Cloxacillin sodium 

Cat. No.: HY-B0466B
Handling Instructions

Cloxacillin sodium exhibits antibiotic efficacy, with a MIC of 256 mg/L for Staphylococcus aureus 25923.

For research use only. We do not sell to patients.

Cloxacillin sodium Chemical Structure

Cloxacillin sodium Chemical Structure

CAS No. : 642-78-4

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Description

Cloxacillin sodium exhibits antibiotic efficacy, with a MIC of 256 mg/L for Staphylococcus aureus 25923[1][2][3].

In Vitro

Cloxacillin is an antibiotic useful for the study of a number of bacterial infections[1].

Cell Viability Assay[1]

Cell Line: Strains M12 and M60.
Concentration: 0.5 μg/mL.
Incubation Time: 4-24 h.
Result: Significantly reduced the bacterial numbers.
In Vivo

Cloxacillin sodium (50 mg/kg, Subcutaneously) results a significant antibiotic efficacy against S. aureus[3]

Animal Model: Mice[2].
Dosage: 10 mg/kg (Pharmacological Analysis).
Administration: Given subcutaneously.
Result: Reached a maximal concentration in plasma of 8.4 μg/mL at 10 min and had a half-life of approximately 15 min.
Animal Model: Mice injected with approximately 2 × 106 CFU of bacteria in 0.1 mL saline were aseptically injected into the right thigh muscle[3].
Dosage: 0–500 mg/kg.
Administration: Subcutaneously in the nuchal region at 1 h after infection.
Result: Resulted in a significant decrease in the number of viable S. aureus measured 18 h thereafter.
Molecular Weight

457.86

Formula

C₁₉H₁₇ClN₃NaO₅S

CAS No.

642-78-4

SMILES

O=C(C(C(C(C=CC=C1)=C1Cl)=NO2)=C2C)N[[email protected]]3[[email protected]](SC(C)4C)([H])N(C3=O)[[email protected]]4C(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

CloxacillinBacterialAntibioticInhibitorinhibitorinhibit

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Cloxacillin sodium
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