CYP51-IN-17
CYP51-IN-17 (compound 7a) is a potent CYP51 inhibitor with an IC50 of 0.377 μg/mL. CYP51-IN-17 shows significant fungicidal activity against B. cinerea with an EC50 of 0.326 μg/mL.
For research use only. We do not sell to patients.
- Formula: C24H20N2O7
- Molecular Weight:448.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
6.25 μg/mL
Compound: 7a
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Cytotoxicity against HEK293 cells incubated for 72 hrs by MTT assay
Cytotoxicity against HEK293 cells incubated for 72 hrs by MTT assay
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[PMID: 38703119] |
Chemical Information
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Molecular Weight 448.42
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Formula C24H20N2O7
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SMILES
O=C(C(C1C2=CC=CO2)=C(N)OC3=C1CN(C(C4=CC=CO4)=O)C/C3=C\C5=CC=CO5)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CYP51-IN-17 Related Classifications
HY-163571 Related Classifications
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