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Art. -Nr.: HY-13735H

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Quinacrine acetate

(Synonyms: Acriquine acetate)

4 Cited Publications

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Based on 4 publication(s) in Google Scholar

Quinacrine (Acriquine) acetate is a small molecule modulator of the cGAS-STING-TBK1 signaling pathway, possessing immune stimulatory activity. Quinacrine acetate has been explored for its potential therapeutic applications in enhancing anti-tumor immunity. Quinacrine acetate can improve the effectiveness of cancer immunotherapies by addressing the poor immunogenicity of various tumors. Quinacrine acetate also presents a promising strategy for overcoming the limitations associated with immune checkpoint inhibitors in cancer treatment.

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CAS. Nr.: 78901-94-7
Formel: C₂₅H₃₄ClN₃O₃
Molecular Weight:460.01

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Quinacrine acetate Chemical Structure

CAS. Nr.: 78901-94-7

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information

CAS. Nr. 78901-94-7
Molecular Weight 460.01
Formel C₂₅H₃₄ClN₃O₃
SMILES

O=C(C)O.ClC(C=CC1=C2NC(CCCN(CC)CC)C)=CC1=NC3=C2C=C(OC)C=C3
Synonyms

Acriquine acetate
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (4)

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J Neuroinflammation

STING activates ZBP1-mediated PANoptosis to defend against HSV-1 retinal infection. [Abstract]

2025 Oct 27;22(1):243. PMID: 41146204
Phytomedicine

Quinacrine induces autophagy via the Dlg5/AKT pathway to inhibit osteosarcoma cell proliferation and suppresses migration and invasion through the Dlg5/Girdin pathway. [Abstract]

2025 Jun 12:145:156981. PMID: 40541124
J Pharm Anal

2025 Dec 15.
Brain Behav Immun

Inhibition of the NFATc2/FKBP5 axis alleviates microglial neuroinflammation by regulating arachidonic acid metabolism in Parkinson's disease. [Abstract]

2026 Jan 18:134:106296. PMID: 41554345

Reinheit & Dokumentation

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Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Small molecules targeting the innate immune cGAS‒STING‒TBK1 signaling pathway [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Quinacrine acetate

4 Cited Publications

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Publications (4)
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Quinacrine acetate

Publications Citing Use of MedChemExpress (MCE) Quinacrine acetate

Alle Parasite Isoform-spezifische Produkte anzeigen

Alle Sodium Channel Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (4)

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Quinacrine acetate Related Classifications

HY-13735H Related Classifications