DH-18
DH-18 is a matrix metalloproteinase-2 (MMP-2) inhibitor with the IC50 values of 139.45 nM, 518.11 nM and 833.34 nM for MMP-2, MMP-9 and MMP-8, respectively. DH-18 induces cell apoptosis and arrests cell cycle in the G0/G1 phase. DH-18 inhibits cell growth and can be used for study of chronic myeloid leukemia.
For research use only. We do not sell to patients.
- Formula: C26H23F6N3O5S
- Molecular Weight:603.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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MMP-2 139.45 nM (IC50) |
MMP-9 518.11 nM (IC50) |
MMP-8 833.34 nM (IC50) |
Chemical Information
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Molecular Weight 603.53
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Formula C26H23F6N3O5S
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SMILES
O=C(NCC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)CCC(C(NO)=O)NS(=O)(C2=CC=C(C=C2)C3=CC=CC=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DH-18 Related Classifications
HY-168605 Related Classifications
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