8CN
8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis.
For research use only. We do not sell to patients.
- CAS No.: 40106-14-7
- Formula: C11H14N2S
- Molecular Weight:206.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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Leishmania |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| J774.A1 | CC50 |
43.9 μM
Compound: 8CN
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Cytotoxicity against mouse J774.A1 cells incubated for 72 hrs by MTT colorimetric assay
Cytotoxicity against mouse J774.A1 cells incubated for 72 hrs by MTT colorimetric assay
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[PMID: 36848847] |
8CN (72 h) has anti-leishmanial activity against the two evolutionary forms of Leishmania amazonensis (amastigotes and promastigotes) with IC50 values of 9.8 and 1.2 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 40106-14-7
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Molecular Weight 206.31
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Formula C11H14N2S
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SMILES
C1CCCC2=C(CC1)C(=C(N)S2)C#N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
8CN Related Classifications
HY-W159102 Related Classifications
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