2. Anti-infection
  3. Parasite
  4. DNDI-0690

DNDI-0690 is a potent orally active analogue of DNDI-VL-2098, exhibiting potent activity against cutaneous leishmaniasis (CL). DNDI-0690 shows potent in vitro activity against CL-causing Leishmania species (EC50 = 0.17 μM against visceral leishmaniasis (VL), and < 5 μM against CL-causing species). DNDI-0690 exerts effects in a mouse model of L. major CL. DNDI-0690 can be used for CL research.

For research use only. We do not sell to patients.

DNDI-0690

DNDI-0690 Chemical Structure

CAS No. : 2097881-13-3

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DNDI-0690 Related Antibodies

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Description

DNDI-0690 is a potent orally active analogue of DNDI-VL-2098, exhibiting potent activity against cutaneous leishmaniasis (CL). DNDI-0690 shows potent in vitro activity against CL-causing Leishmania species (EC50 = 0.17 μM against visceral leishmaniasis (VL), and < 5 μM against CL-causing species). DNDI-0690 exerts effects in a mouse model of L. major CL. DNDI-0690 can be used for CL research[1].

Clinical Trial
Molecular Weight

370.33

Formula

C18H15FN4O4
CAS No.
SMILES

FC(C=C1)=CC=C1C2=NC=C(C=C2)OC[C@@H]3OC4=NC([N+]([O-])=O)=CN4CC3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DNDI-0690 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DNDI-06902097881-13-3DNDI0690DNDI 0690ParasiteDNDI-VL-2098cutaneous leishmaniasisLeishmaniaCLVLInhibitorinhibitorinhibit

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