1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Dup-721

Dup-721 

Cat. No.: HY-139618 Purity: 98.01%
Handling Instructions

DuP-721 is a broad spectrum and orally active antibacterial agent against a variety of clinically susceptible and resistant bacteria, especially M. tuberculosis.

For research use only. We do not sell to patients.

Dup-721 Chemical Structure

Dup-721 Chemical Structure

CAS No. : 104421-21-8

Size Price Stock Quantity
5 mg USD 160 In-stock
Estimated Time of Arrival: December 31
10 mg USD 260 In-stock
Estimated Time of Arrival: December 31
25 mg USD 530 In-stock
Estimated Time of Arrival: December 31
50 mg USD 850 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1330 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

DuP-721 is a broad spectrum and orally active antibacterial agent against a variety of clinically susceptible and resistant bacteria, especially M. tuberculosis[1].

In Vitro

DuP-721 (1.5-4 μg/ml) inhibits equally the strains of Mycobacterium tuberculosis susceptible and resistant to conventional antituberculosis drug. And it does not show cross resistance to any of the anti-tuberculosis drugs tested[1].
DuP-721 is inactive against M. avium and M. intracellulare at 250 μg/ml. It inhibits M. gordonoe and M. fortuitum at 3.9 μg/ml and M. kansassi and M. scrofulaceum at 1.95 μg/ml and 15.6 μg/ml, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

DuP-721 (oral gavage; 50-160 mg/kg) is protective against M. tuberculosis infection in mice. DuP-721 protects 100% of the infected animals at 50 mg/kg p.o. dose when administered daily for 17 days, and the same effect is observed at 160 mg/kg dose when the drug is administered only on day 11 and 12 post infection[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

276.29

Formula

C₁₄H₁₆N₂O₄

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References
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Product Name:
Dup-721
Cat. No.:
HY-139618
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