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Cat. No.: HY-W586108

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EM-12-SH

EM-12-SH is a Cereblon E3 ligand and can be used for the synthesis of PROTACs, such as SIAIS100 (HY-152036).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2378582-39-7
화학식: C₁₃H₁₂N₂O₃S
분자량:276.31

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

EM-12-SH Chemical Structure

CAS No.: 2378582-39-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
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Biological Activity

제품 설명

EM-12-SH is a Cereblon E3 ligand and can be used for the synthesis of PROTACs, such as SIAIS100 (HY-152036)^[1].

IC₅₀ & Target^[1]

Cereblon

All Ligands for E3 Ligase Isoforms :

Chemical Information

CAS No. 2378582-39-7
분자량 276.31
화학식 C₁₃H₁₂N₂O₃S
SMILES

O=C(C(N(CC1=C2C=CC=C1S)C2=O)CC3)NC3=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Liu H, et al. Discovery and characterization of novel potent BCR-ABL degraders by conjugating allosteric inhibitor. Eur J Med Chem. 2022 Dec 15;244:114810. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
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- IC₅₀ & Target
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EM-12-SH

All Ligands for E3 Ligase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

EM-12-SH Related Classifications

HY-W586108 Related Classifications