EMT inhibitor-2
Based on 1 Customer Validation
EMT inhibitor-2 (Compound 1) inhibits epithelial-mesenchymal transition (EMT) induced by substances such as IL-1β and TGF-β released from the immunocytes. EMT inhibitor-2 inhibits CYP3A4 testosteron and CYP2C9 with IC50s of 49.72 and 5.54 μM, respectively.
For research use only. We do not sell to patients.
- Purity: 98.83%
- CAS No.: 2232228-60-1
- Formula: C24H26N2O8
- Molecular Weight:470.47
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Metabolism/Protease Compound Library
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Biological Activity
Chemical Information
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CAS No. 2232228-60-1
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Appearance Solid
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Molecular Weight 470.47
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Formula C24H26N2O8
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Color Off-white to light yellow
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SMILES
COC1=C(O)C2=C(OC(C3=CC=C(OC)C(OC)=C3)=CC2=O)C=C1OCCN(C4)CCNC4=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 83.33 mg/mL (177.12 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1255 mL | 10.6277 mL | 21.2553 mL | 53.1384 mL |
| 5 mM | 0.4251 mL | 2.1255 mL | 4.2511 mL | 10.6277 mL | |
| 10 mM | 0.2126 mL | 1.0628 mL | 2.1255 mL | 5.3138 mL | |
| 15 mM | 0.1417 mL | 0.7085 mL | 1.4170 mL | 3.5426 mL | |
| 20 mM | 0.1063 mL | 0.5314 mL | 1.0628 mL | 2.6569 mL | |
| 25 mM | 0.0850 mL | 0.4251 mL | 0.8502 mL | 2.1255 mL | |
| 30 mM | 0.0709 mL | 0.3543 mL | 0.7085 mL | 1.7713 mL | |
| 40 mM | 0.0531 mL | 0.2657 mL | 0.5314 mL | 1.3285 mL | |
| 50 mM | 0.0425 mL | 0.2126 mL | 0.4251 mL | 1.0628 mL | |
| 60 mM | 0.0354 mL | 0.1771 mL | 0.3543 mL | 0.8856 mL | |
| 80 mM | 0.0266 mL | 0.1328 mL | 0.2657 mL | 0.6642 mL | |
| 100 mM | 0.0213 mL | 0.1063 mL | 0.2126 mL | 0.5314 mL |
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