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Referencia número: HY-179118

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Antimalarial agent 53

Antimalarial agent 53 (compound 31) is an antimalarial agent. Antimalarial agent 53 blocks protein synthesis by inhibiting the cytoplasmic ribosomes of malaria parasites, exhibiting potent antimalarial activity (IC₅₀ = 3.9 nM) and good selectivity. Antimalarial agent 53 has no cross resistance and good safety. Antimalarial agent 53 can be used for research on malaria.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₂₄H₂₄F₃N₅O₃
Peso molecular:487.47

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Antimalarial agent 53 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas Parasite :

Chemical Information

Peso molecular 487.47
Fòrmula C₂₄H₂₄F₃N₅O₃
SMILES

O=C(NC1=CC(NN2CCN(C)CC2)=CC=C1O)C3=CC(OC4=CC(C(F)(F)F)=CC=N4)=CC=C3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Bravo P, et al. A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum. Angew Chem Int Ed Engl. 2025 Oct 20:e202514085. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
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Chemical Information
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Antimalarial agent 53

Ver todos los productos específicos de isoformas Parasite

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Antimalarial agent 53 Related Classifications

HY-179118 Related Classifications