Floramanoside F
Floramanoside F is a type of flavonol glycoside compound. Floramanoside F has a moderate free radical scavenging effect, with a SC₅₀ value of 25.1 μM. Floramanoside F has a relatively weak inhibitory activity on aldose reductase, with a IC₅₀ value greater than 100 μM. Floramanoside F has strong binding affinity with key target enzymes of type 1 diabetic nephropathy (T1DN) (Fasn, Cyp2e1, Cyp4a32), and can inhibit lipid accumulation and oxidative stress, thereby alleviating renal inflammation and fibrosis. Floramanoside F can be used to study type 1 diabetic nephropathy and diabetic complications.
For research use only. We do not sell to patients.
- CAS No.: 1487423-58-4
- Formula: C23H22O14
- Molecular Weight:522.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1487423-58-4
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Molecular Weight 522.41
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Formula C23H22O14
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SMILES
O=C(C(O)=C(C1=CC(O)=C(C=C1)O)O2)C(C2=C3O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(OCC)=O)=C(C=C3O)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yan X, et al. Exploring the molecular mechanisms for renoprotective effects of Huangkui capsule on diabetic nephropathy mice by comprehensive serum metabolomics analysis. J Ethnopharmacol. 2025;340:119223. [Content Brief]
[2]. Zhang Y, et al. Antioxidative flavonol glycosides from the flowers of Abelmouschus manihot. J Nat Med. 2013;67(1):78-85. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)