LUF8100
Based on 1 Customer Validation
LUF8100 is a dual-target antagonist of CCR2/CCR5 with pKi values for CCR2 and CCR5 of 5.23 and 4.97 respectively. LUF8100 can be used for research on immune homeostasis and cancer.
For research use only. We do not sell to patients.
- Purity: 98.64%
- CAS No.: 2954281-30-0
- Formula: C18H18ClF3N2O2S
- Molecular Weight:418.86
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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CCR2 5.23 (pKi) |
CCR5 4.97 (pKi) |
Chemical Information
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CAS No. 2954281-30-0
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Appearance Solid
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Molecular Weight 418.86
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Formula C18H18ClF3N2O2S
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Color Off-white to pink
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SMILES
O=S(NC1=CC(N2CCCCC2)=CC=C1)(C3=CC=C(Cl)C(C(F)(F)F)=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (238.74 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3874 mL | 11.9372 mL | 23.8743 mL | 59.6858 mL |
| 5 mM | 0.4775 mL | 2.3874 mL | 4.7749 mL | 11.9372 mL | |
| 10 mM | 0.2387 mL | 1.1937 mL | 2.3874 mL | 5.9686 mL | |
| 15 mM | 0.1592 mL | 0.7958 mL | 1.5916 mL | 3.9791 mL | |
| 20 mM | 0.1194 mL | 0.5969 mL | 1.1937 mL | 2.9843 mL | |
| 25 mM | 0.0955 mL | 0.4775 mL | 0.9550 mL | 2.3874 mL | |
| 30 mM | 0.0796 mL | 0.3979 mL | 0.7958 mL | 1.9895 mL | |
| 40 mM | 0.0597 mL | 0.2984 mL | 0.5969 mL | 1.4921 mL | |
| 50 mM | 0.0477 mL | 0.2387 mL | 0.4775 mL | 1.1937 mL | |
| 60 mM | 0.0398 mL | 0.1990 mL | 0.3979 mL | 0.9948 mL | |
| 80 mM | 0.0298 mL | 0.1492 mL | 0.2984 mL | 0.7461 mL | |
| 100 mM | 0.0239 mL | 0.1194 mL | 0.2387 mL | 0.5969 mL |
LUF8100 Related Classifications
HY-179607 Related Classifications
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