AP-22161
AP22161 is a potent and selective Src SH2 domain inhibitor with an IC50 of 0.24 µM. AP22161 exhibits >120-fold selectivity over Yes SH2 (IC50 = 29.38 µM) and ZAP SH2 (IC50 = 421.86 µM). AP22161 inhibits Src-dependent cellular activity and diminishes osteoclast resorptive activity. AP22161 can be used for osteoporosis research.
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- No. CAS: 268741-42-0
- Fòrmula: C32H39N3O7
- Peso molecular:577.67
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
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Yes SH2 29.38 μM (IC50) |
ZAP SH2 421.86 μM (IC50) |
Chemical Information
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No. CAS 268741-42-0
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Peso molecular 577.67
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Fòrmula C32H39N3O7
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SMILES
O=C(O)C1=CC=C(C[C@H](NC(C)=O)C(N[C@H]2CCCCC3=CC(OCC4CCCCC4)=C(C(N)=O)C=C32)=O)C=C1C=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AP-22161 Related Classifications
HY-123394 Related Classifications
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