Callophycin A
Callophycin A, a red seaweed derived metabolite, possessing potent activity against Candida albicans with MIC of 62.5~250 mg/L. Callophycin A significantly reduces fungal burden of vaginal candidiasis induced mice, also decreases inflammatory response and immune molecules.
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- No. CAS: 1345674-93-2
- Fòrmula: C19H18N2O3
- Peso molecular:322.36
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
MIC: 62.5~250 mg/L (Candida albicans)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female Swiss albino mice (infected with Candida albicans)[1]
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Dosage:1%
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Administration:For 5 days
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Result:Dramatically reduces CFU of Candida albicans from about 400 to 100/ml; and significantly (p < 0.001) reduces the amount of IL-6 (2.71 ± 0.09 to 1.83 ± 0.03 pg/µl), IL-12 (7.33 ± 0.15 to 6.13 ± 0.15 pg/µl), IL-17 (17.83 ± 0.21 to 13.70 ± 0.2 pg/µl) and IL-22 (5.33 ± 0.25 to 4.20 ± 0.26 pg/µl) compared with disease control group.
Chemical Information
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No. CAS 1345674-93-2
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Peso molecular 322.36
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Fòrmula C19H18N2O3
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SMILES
O=C(C1CC2=C(CN1CC3=CC=C(O)C=C3)NC4=C2C=CC=C4)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Callophycin A Related Classifications
HY-146190 Related Classifications
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