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Referencia número: HY-N20729

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Eucommin A

Eucommin A is a natural polyphenolic antioxidant. Eucommin A forms stable complexes with EGFR and MAPK8 via hydrogen bonding and hydrophobic interactions, and regulates osteoarthritis-related Autophagy. Eucommin A is applicable to research related to oxidative stress, such as osteoarthritis.

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No. CAS: 99633-12-2
Fòrmula: C₂₇H₃₄O₁₂
Peso molecular:550.56

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Eucommin A Chemical Structure

No. CAS: 99633-12-2

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One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
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Bioz

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas EGFR :

Ver todos los productos específicos de isoformas p38 MAPK :

In Vitro

Eucommin A binds tightly to purified human EGFR protein and human MAPK8 protein via multiple hydrogen bonds, with binding energies of -7.8 kcal/mol and -9.1 kcal/mol^[1].
Eucommin A is a polyphenolic component with in vitro antioxidant activity^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 99633-12-2
Peso molecular 550.56
Fòrmula C₂₇H₃₄O₁₂
SMILES

O(C)C=1C=C([C@@H]2[C@@]3([C@@]([C@H](OC3)C4=CC(OC)=C(O)C=C4)(CO2)[H])[H])C=C(OC)C1O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Yage Zhang, et al. Bioinformatics-based identification of autophagy-related key genes in osteoarthritis and therapeutic potential analysis of Eucommin A[J]. Journal of Chinese Pharmaceutical Sciences, 2025, 34(9): 831-849.

[2]. Boubertakh H, et al. RP-UHPLC-ESI-QTOF-MSⁿ analyses, antioxidant, antimicrobial, analgesic activities and toxicity of Achillea ligustica All. Natural Product Research, 2025, 39(11): 3316-3321.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Eucommin A

Ver todos los productos específicos de isoformas EGFR

Ver todos los productos específicos de isoformas p38 MAPK