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Referencia número: HY-119764

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Ikarugamycin

2 Cited Publications

Revisión del cliente

Based on 2 publication(s) in Google Scholar

Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME).

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: 99.9%
No. CAS: 36531-78-9
Fòrmula: C₂₉H₃₈N₂O₄
Peso molecular:478.62

Almacenamiento:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Ikarugamycin Chemical Structure

No. CAS: 36531-78-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- IC₅₀ & Target
- In Vitro
Chemical Information
Publications (2)
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Bioz

Actividad biológica

Descripciòn

Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME)^[1].

IC₅₀ & Target

Clathrin-mediated endocytosis^[1]

Ver todos los productos específicos de isoformas Antibiotic :

In Vitro

Ikarugamycin has an IC₅₀ of 2.7 μM in H1299 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 36531-78-9
Appearance Solid
Peso molecular 478.62
Fòrmula C₂₉H₃₈N₂O₄
Color White to light yellow
SMILES

O=C(/C=C/[C@@H]1C[C@]2([C@@]([H])([C@H]1C/C=C\3)C=C[C@@]4([C@@]2(C[C@H]([C@H]4CC)C)[H])[H])[H])C5=C([C@@H](NC5=O)CCCNC3=O)O
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Streptomyces species
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Publications (2)

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Journal Impact Factor

J Extracell Vesicles

Cdc42 functions as a regulatory node for tumour-derived microvesicle biogenesis. [Abstract]

2021 Jan;10(3):e12051. PMID: 33473262
J Immunother Cancer

Anticancer effects of ikarugamycin and astemizole identified in a screen for stimulators of cellular immune responses. [Abstract]

2023 Jul;11(7):e006785. PMID: 37419511

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (274 KB)
SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Elkin SR, et al. Ikarugamycin: A Natural Product Inhibitor of Clathrin-Mediated Endocytosis. Traffic. 2016 Oct;17(10):1139-49. [Content Brief]

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Ikarugamycin

2 Cited Publications

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Actividad biológica
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- In Vitro
Chemical Information
Publications (2)
Pureza y Documentación
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Ikarugamycin

Publications Citing Use of MedChemExpress (MCE) Ikarugamycin

Ver todos los productos específicos de isoformas Antibiotic

Actividad biológica

Chemical Information

Publications (2)

Pureza y Documentación

Referencias

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Ikarugamycin Related Classifications

HY-119764 Related Classifications