Lavoltidine
Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia.
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- No. CAS: 76956-02-0
- Fòrmula: C19H29N5O2
- Peso molecular:359.47
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Ver todos los productos específicos de isoformas Histamine Receptor
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Actividad biológica
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H2 Receptor |
Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis[1]
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Dosage:0.5 g/L
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Administration:Orally (drinking water); changed weekly; for 3 months
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Result:Showed partial suppression of both gastric acid secretion and progression to neoplasia.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 76956-02-0
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Peso molecular 359.47
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Fòrmula C19H29N5O2
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SMILES
OCC1=NN(C(NCCCOC2=CC=CC(CN3CCCCC3)=C2)=N1)C
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Synonyms
Loxtidine; AH-234844
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lavoltidine Related Classifications
HY-121450 Related Classifications
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