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Referencia número: HY-105488

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MDL 201112

MDL 201112 is a carbocyclic nucleoside. MDL 201112 can decrease TNF-α production and inhibit MHC class II Ia+ antigen expression. MDL 201112 can be used for the research of inflammation and immunology.

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No. CAS: 142130-73-2
Fòrmula: C₁₀H₁₃N₅O
Peso molecular:219.24

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

MDL 201112 Chemical Structure

No. CAS: 142130-73-2

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Descripciòn

IC₅₀ & Target^[1]

MHC II

Ver todos los productos específicos de isoformas TNF Receptor :

Ver todos los productos específicos de isoformas MHC :

MHC I
MHC II

In Vitro

MDL 201112 (10 μM) decreases TNF-α production and inhibits MHC class II Ia+ antigen expression in LEW/N m phi^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 142130-73-2
Peso molecular 219.24
Fòrmula C₁₀H₁₃N₅O
SMILES

NC1=NC=NC2=C1N=CN2[C@@H]3C[C@H](O)CC3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Edwards CK 3rd, et al. Effect of the carbocyclic nucleoside analogue MDL 201,112 on inhibition of interferon-gamma-induced priming of Lewis (LEW/N) rat macrophages for enhanced respiratory burst and MHC class II Ia+ antigen expression. J Leukoc Biol. 1994 Aug;56(2):133-44. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MDL 201112

Ver todos los productos específicos de isoformas TNF Receptor

Ver todos los productos específicos de isoformas MHC

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

MDL 201112 Related Classifications

HY-105488 Related Classifications