MK 1256
MK 1256 is a highly selective and orally active inhibitor of tissue protease K (Cat K) with an IC50 of 0.62 nM. MK 1256 shows extremely high selectivity towards other tissue proteases (all > 1100 times), with only a slightly lower selectivity for tissue protease F (Cat F) (110 times). MK 1256 exhibits strong anti-bone resorption activity in the osteoporosis model of rhesus monkeys with ovariectomy. MK 1256 can be used for research on osteoporosis.
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- No. CAS: 919109-76-5
- Fòrmula: C23H23Cl2F3N4O3S
- Peso molecular:563.42
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 919109-76-5
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Peso molecular 563.42
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Fòrmula C23H23Cl2F3N4O3S
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SMILES
O=C([C@H]1[C@H](C2=NN(CC(F)(F)F)C=C2C3=CC=C(S(=O)(C)=O)C=C3)CCC(Cl)(Cl)C1)NC4(C#N)CC4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MK 1256 Related Classifications
HY-14360 Related Classifications
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