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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2438 Results for "
decrease
" in MedChemExpress (MCE) Product Catalog:
Products (2438)
2438 Results for "decrease" in MCE Product Catalog:
Referencia número: HY-134579
No. CAS: 148796-51-4
Category:
Target:
Referencia número: HY-137162
No. CAS: 84625-59-2
Áreas de investigación:
Dotarizine is a novel Piperazine (HY-B0912) derivative and antimigraine agent. Dotarizine exhibits Ca 2+ channel blocking properties. Dotarizine decreases the release of lactate dehydrogenase. Dotarizine shows 5-HT receptor blocking effect .
Referencia número: HY-147013
No. CAS: 13878-10-9
Target:
Áreas de investigación:
Caprochlorone has antiviral activity against orthopoxvirus. Caprochlorone can inhibit cell penetration by virus, also delays release of newly formed virus from the cell. Caprochlorone decreases the titers of influenza virus in infected-mice lungs .
Referencia número: HY-149232
No. CAS: 2935903-77-6
HPK1-IN-35 is a potent and selective HPK1 inhibitor with an IC50 value of 3.5 nM. HPK1-IN-35 decreases the expression of p-SLP76 and promotes IL-2 secretion .
Referencia número: HY-150655
No. CAS: 2252283-32-0
Hsp90-IN-15 is an Hsp90 inhibitor with anticancer activity. Hsp90-IN-15 induces cell apoptosis, arrests the cell cycle at S phase and decreases the expression level of Hsp90 in Hela cell .
Target:
Áreas de investigación:
SPOP-IN-1 is a selective SPOP E3 ubiquitin ligase inhibitor. SPOP-IN-1 leads to the accumulation of tumor suppressors PTEN and DUSP7 and decreased levels of phosphorylated AKT and ERK in clear-cell renal cell carcinoma .
Referencia número: HY-170967
Áreas de investigación:
IPH10 is an anti-cancer agent that exhibits a strong anti-tumor effect in vivo without hepatic and renal toxicity. IPH10 can significantly increase the content of ROS, decrease the mitochondrial membrane potential, and induce apoptosis in tumor cells .
Referencia número: HY-N11772
No. CAS: 875455-92-8
Category:
Target:
Synonyms: Senecionan-11,16-dione, 12-hydroxy-; Aureine; Senecionin
Category:
Alkaloids Senecio scandens Buch.-Ham. ex D. Don Extract Plant Pyrrole Alkaloids Senecio vulgaris L. Extract Metabolic Disease Compositae/Asteraceae Extract Disease Research Fields
Target:
Referencia número: HY-N2592
No. CAS: 52438-12-7
Category:
Quinones Plant Boraginaceae Extract Phenols Polyphenols Disease Research Fields Inflammation/Immunology Lithospermum canescens Lehm. Extract Naphthalene Quinones
Target:
Referencia número: HY-P10166
No. CAS: 209251-66-1
Target:
Áreas de investigación:
Referencia número: HY-P4815
No. CAS: 423206-00-2
Target:
Áreas de investigación:
Target:
Áreas de investigación:
Ceranib1 is a ceramidase inhibitor. Ceranib1 inhibits ceramidase activity toward an exogenous ceramide analog, induces the accumulation of multiple ceramide species, decreases levels of sphingosine and S1P. Ceranib1 inhibits the proliferation of ovarian cancer cells .
Referencia número: HY-103372R
No. CAS: 685506-42-7
Target:
Áreas de investigación:
GSK264220A (Standard) is the analytical standard of GSK264220A (HY-103372). This product is intended for research and analytical applications. GSK264220A is a potent endothelial lipase inhibitor with IC50 of 16 nM. GSK264220A has the potential to decrease the risk of cardiovascular disease .
Referencia número: HY-112598
No. CAS: 1900686-46-5
Target:
Áreas de investigación:
PF-06815345 is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with an IC50 value of 13.4 μM. PF-06815345 significantly decreases the PCSK9 level in vivo in mouse .
Target:
Áreas de investigación:
PF-06815345 hydrochloride is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with an IC50 value of 13.4 μM. PF-06815345 hydrochloride significantly decreases the PCSK9 level in vivo in mouse .
Referencia número: HY-114941
No. CAS: 173429-64-6
Synonyms: BP1137
Áreas de investigación:
Aladotril (BP1137) is the inhibitor for neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE), that ameliorates the cardiac hypertrophy in rats, without decreasing the blood pressure. Aladotril can be used in research about heart failure and cardiac remodeling after myocardial infarction .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
