41 Results for "

TRAIL-R

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "TRAIL-R" in MCE Product Catalog:

1
1 Cited Publications
Referencia número: HY-P99934
No. CAS: 1820660-69-2
Synonyms: ABBV-621

Áreas de investigación:  

Cancer

Eftozanermin alfa (ABBV-621) is a tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa is a fusion protein consisting of a mutant immunoglobulin G1-Fc linked to 2 single-chain trimers of TRAIL. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors (DR4 receptor and DR5 receptor) with Kds of 780 nM and 635 nM. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies .
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Referencia número: HY-P99260
No. CAS: 896731-82-1
Synonyms: AMG 655; TRAIL-R2 mAb; Human Anti-TNFRSF10B Recombinant Antibody

Target:  

TNF Receptor

Áreas de investigación:  

Cancer

Conatumumab (AMG 655) is a human monoclonal agonist antibody against human death receptor 5 (DR5, TRAILR2) (Kd: 1 nM for the long form of DR5, 0.8 nM for the short form of DR5). Conatumumab induces apoptosis via caspase activation. Conatumumab can be used in the research of cancers. .
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Referencia número: HY-148875
No. CAS: 2247398-68-9
Pureza:  99.78%
Áreas de investigación:  

Cancer

Py-MAA-Val-Cit-PAB-MMAE is a drug-Linker conjugates for ADC, which is composed of MMAE (HY-15162) and Py-MAA-Val-Cit-PAB linked. Py-MAA-Val-Cit-PAB-MMAE can be used to synthesize Zapadcine-3a, which targeting TRAILR2. Zapadcine-3a has broad-spectrum anti-tumor activity, and can specifically kill TRAILR2-positive tumors .
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Referencia número: HY-P99299
No. CAS: 845816-02-6
Synonyms: HGS-ETR 2; ETR2-ST01

Target:  

Apoptosis

Áreas de investigación:  

Cancer

Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research .
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Referencia número: HY-P99270
No. CAS: 918127-53-4
Synonyms: CS-1008; Anti-Human TRAIL-R2 Recombinant Antibody

Target:  

Apoptosis

Áreas de investigación:  

Cancer

Tigatuzumab (CS-1008) is a humanized IgG1 monoclonal antibody targets death receptor 5 (DR5). Tigatuzumab induces cell apoptosis of cancer cells and inhibits tumor growth in vivo. Tigatuzumab can be used for the research of cancer .
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Referencia número: HY-P99265
No. CAS: 658052-09-6
Synonyms: HGS-ETR1; Anti-Human TNFRSF10A Recombinant Antibody

Target:  

Inhibitory Antibodies

Áreas de investigación:  

Cancer

Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer .
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Referencia número: HY-P78529
Pureza:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365
Species:  
Source:  
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Referencia número: HY-P78219
Pureza:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365
Species:  
Source:  
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Referencia número: HY-P84855
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Monkey

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Referencia número: HY-P84856
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Mouse

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Referencia número: HY-P84855A
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Monkey

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Referencia número: HY-P84856A
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Mouse

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Referencia número: HY-P78567
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF10B; TRAILR2; TRAIL-R2; CD262; DR5; KILLER; TRICK2; ZTNFR9; TRICKB
Species:  
Source:  
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Referencia número: HY-P74497
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10B; CD262; TRAIL-R2; DR5; KILLER; TRAILR2; ZTNFR9
Species:  
Source:  
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Referencia número: HY-P74498
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10B; CD262; TRAIL-R2; DR5; KILLER; TRAILR2; ZTNFR9
Species:  
Source:  
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Referencia número: HY-P72779
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9
Species:  
Source:  
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Referencia número: HY-P76863
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL-R4; CD264; TRUNDD
Species:  
Source:  
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Referencia número: HY-P72439
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL receptor 4; TRAIL-R4; CD264; TNFRSF10D; DCR2; TRAILR4; TRUNDD
Species:  
Source:  
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Referencia número: HY-P76865
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL-R4; CD264; TRUNDD
Species:  
Source:  
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Referencia número: HY-P76864
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL-R4; CD264; TRUNDD
Species:  
Source:  
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