VU0366248
VU0366248 is a mGlu5 negative allosteric modulator.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1243310-20-4
- Fòrmula: C14H7ClF2N2O
- Peso molecular:292.67
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
|
mGluR5 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293-A | IC50 |
347 nM
Compound: 41
|
Antagonist activity at rat mGlu5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium mobilization
Antagonist activity at rat mGlu5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium mobilization
|
[PMID: 20598884] |
Chemical Information
-
No. CAS 1243310-20-4
-
Peso molecular 292.67
-
Fòrmula C14H7ClF2N2O
-
SMILES
O=C(C1=CC(F)=CC(C#N)=C1)NC2=CC=CC(Cl)=C2F
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)