Fpr2 - formyl peptide receptor 2 Gene

Also Known as Fpr-rs2; E330010I07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14289

Summary

Enables N-formyl peptide receptor activity and amyloid-beta binding activity. Involved in cellular response to amyloid-beta; positive chemotaxis; and positive regulation of superoxide anion generation. Acts upstream of or within Phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Orthologous to human FPR2 (formyl peptide receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Fpr2 Products (1)

mRNA Protein Name
NM_008039.2 NP_032065.1 formyl peptide receptor 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables N-formyl peptide receptor activity IDA
IDA: Inferred from direct assay
22859307 MGI
enables amyloid-beta binding IPI
IPI: Inferred from physical interaction
11316806 MGI
enables signaling receptor activity IDA
IDA: Inferred from direct assay
12218158 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to amyloid-beta IDA
IDA: Inferred from direct assay
11316806 MGI
acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
22859307 MGI
involved in positive chemotaxis IGI
IGI: Inferred from genetic interaction
11316806 MGI
involved in positive regulation of superoxide anion generation IGI
IGI: Inferred from genetic interaction
11316806 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

formyl peptide receptor 2

  • N-formylpeptide receptor-like 2

  • formyl peptide receptor, related sequence 2

  • formylpeptide receptor-related sequence 2

  • lipoxin A4 receptor-like protein

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-131180 BMS-986235 99.84% Phase 1
HY-124071 ACT-389949 98.42% Phase 1

Pre-clinical Phase

Bioactive Molecules (21)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1120 WKYMVm 99.74% Unkown
HY-103286 PD176252 Antagonist 99.38% Unkown
HY-19574 FPR Agonist 43 99.79% Unkown
HY-116216 PD 168368 Antagonist ≥99.0% Unkown
HY-P1744 N-Formyl-Met-Leu-Phe-Lys 99.83% Unkown
HY-P1117 MMK1 99.71% Unkown
HY-W668775 Quin-C7 Antagonist 99.76% Unkown
HY-155335 FPR2 agonist 3 Agonist 99.39% Unkown
HY-144604 FPR2 agonist 2 Agonist 98.51% Unkown
HY-110246 Quin C1 Agonist 98.47% Unkown
HY-P1120A WKYMVm TFA / Unkown
HY-159583 FPR2 agonist 4 Agonist / Unkown
HY-178144 FPR2 agonist 5 / Unkown
HY-181822 BMS-986331 / Unkown
HY-183952 FPR2/ALXR agonist-1 Agonist / Unkown
HY-184654 MR-39 / Unkown
HY-P10432 SHAAGtide Activator / Unkown
HY-P1117A MMK1 TFA / Unkown
HY-RS05086 FPR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16582 Fpr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23016 Fpr2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fpr2 NCBI NCBI:2358