Ulk1 - unc-51 like autophagy activating kinase 1 Gene

Rattus norvegicus

Gene ID: 360827 | Gene type: protein coding

About Ulk1

Primary_assembly 12: 45,851,710-45,877,966 forward strand.mRatBN7.2:CM026985.1

This gene has 2 transcripts (splice variants), 202 orthologues, 2 paralogues and is associated with 3 phenotypes. Biased expression in Heart (RPKM 81.8), Adrenal (RPKM 77.1) and 9 other tissues.

Summary

Predicted to enable several functions, including HSP90 protein binding activity; Enzyme binding activity; and identical protein binding activity. Involved in neuron projection regeneration and positive regulation of autophagosome assembly. Located in axon. Used to study mucositis. Orthologous to human ULK1 (unc-51 like Autophagy activating kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ulk1 Products(1)

mRNA	Protein	Name
NM_001108341.1	NP_001101811.1	serine/threonine-protein kinase ULK1

Ulk1 Protein Structure

STKc_ULK1

DUF3543

0
200
400
600
800
1000
1057 a.a.

Protein Preferred Names

Protein Names

serine/threonine-protein kinase ULK1

unc-51-like kinase 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (14)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-16966	SBI-0206965	Inhibitor	99.39%	Unkown
HY-13018	MRT67307	Inhibitor	99.34%	Unkown
HY-114490	ULK-101	Inhibitor	99.96%	Unkown
HY-124729	BL-918	Activator	99.98%	Unkown
HY-137742	SBP-7455	Inhibitor	98.24%	Unkown
HY-148063	DB0614		98.80%	Unkown
HY-143466	ULK1-IN-2	Inhibitor	99.09%	Unkown
HY-137506	XST-14	Inhibitor	99.69%	Unkown
HY-148061	DB1113		99.28%	Unkown
HY-160699	DCC-3116	Inhibitor	/	Unkown
HY-101923A	LYN-1604 hydrochloride	Activator	/	Unkown
HY-13018A	MRT67307 hydrochloride	Inhibitor	/	Unkown
HY-101923	LYN-1604	Activator	/	Unkown
HY-162100	MR-2088	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ulk1	NCBI	NCBI:8408

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